MORTALIDAD Y RIESGO CARDIOVASCULAR EN VASCULITIS ANCA. IMPORTANCIA DE LA HIPERTENSION Y FUNCION RENAL. EXPERIENCIA DEL SUR DE ESPAÑA

1. Martin-Gómez MA, Rodríguez Torres A, Espinosa Hernández M, Lopez Mendoza M, Sánchez Sánchez JM, Martin Armada M, et al. Mortality and cardiovascular risk in vasculitis ANCA. Importance of hypertension and renal function. Experience from southern Spain. Hipertensión y Riesgo Vascular [Internet]. 2023 jul 28 [citado 2023 ago 4]; doi:10.1016/j.hipert.2023.06.001. Background Cardiovascular disease (CVD) is one of the principal causes of death in antineutrophil cytoplasmic antibody-(ANCA)-associated vasculitis (AAV). Objectives To evaluate the mortality and it’s causes and CVD and its vascular risk factors (VRFs) in AAV patients in Andalusia. Methods A multicenter cohort of 220 AAV patients followed-up from 1979 until June 2020 was studied in Andalussia, south of Spain. The information, including socio-demographic and clinical data was recorded retrospectively through chart review. Data was analysed using Chi2, ANOVA and Cox proportional hazards regresion as uni and multivariate test with a 95% confidence interval (CI). Results During a mean ± standard deviation follow-up of 96.79 ± 75.83 months, 51 patients died and 30 presented at least one CVE. Independent prognostic factors of mortality were age (HR 1.083, p=0.001) and baseline creatinine (HR 4.41, p=0.01). Independent prognostic factors of CVE were age [hazard ratio (HR) 1.042, p=0.005] and the presence of hypertension

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